Tumor in der Prostata

Prostate Cancer Animation

Katheter nach einem Prostata-Operation

Der Pathologe. Tumor in der Prostata vielen Tumorentitäten, insbesondere der Mamma, versteht man unter einem intraduktalen Karzinom eine Vorläuferläsion, die fakultativ der Entstehung eines invasiven Karzinoms vorausgeht. Gerade auch in der Mammadiagnostik spielen Angaben zur Ausdehnung und Beschaffenheit einer intraduktalen Tumorkomponente neben den Parametern des invasiven Karzinoms seit jeher eine besondere, die Therapieplanung modulierende Rolle.

Anders verhält es sich bei der Prostata, bei der der gleiche Begriff zwar existiert und von wenigen seit längerem propagiert, aber dennoch selten und uneinheitlich verwendet wird. Dies liegt zum einen sicher in den vereinfachten Therapieoptionen des Prostatakarzinoms, bei dem fokale und organerhaltende Therapien eine bislang noch untergeordnete Rolle spielen, sicher aber auch in der erheblichen Interobservervariabilität und dem uneinheitlichen Verständnis des intraduktalen Karzinoms.

Dieser kleine Artikel Tumor in der Prostata eine Übersicht über die gegenwärtige Literatur zum Thema geben und erläutern, warum es sich lohnt, diese Läsion zu diagnostizieren. Im Gegensatz zur Mamma stellt das intraduktale Karzinom bei der Prostata ganz überwiegend eine postinvasive Läsion dar, bei der ein dazu geeigneter, zumeist aggressiver Tumor in das präexistente Gangsystem einbricht.

Seltener scheint es sich jedoch auch um eine echte Vorläuferläsion handeln zu können. For many tumor entities, especially in breast cancer, an intraductal carcinoma is generally perceived as a precursor Tumor in der Prostata, which precedes the emergence of invasive carcinoma. Therefore, in addition to parameters of the invasive carcinoma, histological parameters Tumor in der Prostata the intraductal component have always played an important role in therapy planning of breast cancer.

This is different in prostate cancer and although the term "intraductal carcinoma" has long been propagated by some authors, its routine use remains rare and inconsistent. This is certainly not only due to the far simpler therapy options of prostate cancer, in which focal and organ-preserving therapies still play a subordinate role, but also Tumor in der Prostata to substantial interobserver variation and our inconsistent perception of intraductal carcinomas.

This article gives a brief overview of currently available literature on this topic and explains why intraductal carcinoma of the prostate deserves our attention. In contrast to breast cancer, intraductal carcinoma of the prostate usually represents Tumor in der Prostata post-invasive lesion, in which an aggressive tumor exhibits spread into pre-existing ducts; however, in rare cases, intraductal carcinoma may represent a true precursor lesion.

Kristiansen, M. Varma und G. Seitz geben an, dass kein Interessenkonflikt besteht. Skip to main content. Advertisement Hide. Intraduktales Karzinom der Prostata.

Authors Authors and affiliations G. Kristiansen M. Varma G. Schwerpunkt: Uropathologie First Online: 18 January Intraductal carcinoma of the prostate. This is a preview of subscription content, log in to check access. Einhaltung ethischer Richtlinien Interessenkonflikt G. Anonymous Pathology and genetics of tumours of the urinary system and male genital organs. Tumor in der Prostata — CrossRef Google Scholar. Clouston D, Bolton D In situ and intraductal epithelial proliferations of prostate: definitions and treatment implications.

Part 2: intraductal Tumor in der Prostata and ductal adenocarcinoma of prostate. Cohen RJ, Wheeler TM, Bonkhoff H et al A proposal on the identification, histologic reporting, and implications of intraductal prostatic carcinoma. Guo CC, Epstein JI Intraductal carcinoma of the prostate on needle biopsy: histologic features and clinical significance. Humphrey PA Intraductal carcinoma of the prostate. Iczkowski KA, Egevad L, Ma J et al Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists.

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Tumor in der Prostata V, Kristiansen G Histopathological screening for prostate carcinoma: is a benign biopsy a negative biopsy? Shah RB, Zhou M Atypical cribriform lesions of the prostate: clinical significance, differential diagnosis and current concept of intraductal carcinoma of the prostate. Trudel D, Downes MR, Sykes J et al Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary Tumor in der Prostata.

Tsuzuki T Intraductal carcinoma of the prostate: a comprehensive and updated review. Tumor in der Prostata Der Kwast T, Al Daoud N, Collette L et al Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy.

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Kristiansen 1 Email author M. Varma 2 G. Seitz 3 1. Personalised recommendations. Cite article How to cite? ENW EndNote. Buy options.